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Publications 2010

(26)    Yougnia, R.; Rochais, C.; Oliveira Santos, J. S.; Dallemagne, P.; Rault, S. One-Pot Synthesis of Novel Poly-Substituted Phenanthrenes. Tetrahedron 2010, 66, 2803–2808.

(25)    Voisin-Chiret, A. S.; Muraglia, M.; Burzicki, G.; Perato, S.; Corbo, F.; Sopková-De Oliveira Santos, J.; Franchini, C.; Rault, S. Synthesis of New Phenylpyridyl Scaffolds Using the Garlanding Approach. Tetrahedron 2010, 66, 8000–8005.

(24)    Varin, T.; Gutiérrez-De-Terán, H.; Castro, M.; Brea, J.; Fabis, F.; Dauphin, F.; Åqvist, J.; Lepailleur, A.; Perez, P.; Burgueño, J.; Vela, J. M.; Loza, M. I.; Rodrigo, J. Phe369(7.38) at Human 5-HT7 Receptors Confers Interspecies Selectivity to Antagonists and Partial Agonists. Br. J. Pharmacol. 2010, 159, 1069–1081.

(23)    Sopková-De Oliveira Santos, J.; Primas, N.; Lohier, J. F.; Bouillon, A.; Rault, S. An Inter-Molecular Dative BN Bond in 5-(4,4,5,5-Tetramethyl-1,3,2- Dioxaborolan-2-Yl)-1,3-Thiazole. Acta Crystallogr. Sect. E Struct. Reports Online 2010, 66.

(22)    Sopkova-de Oliveira Santos, J.; Lesnard, A.; Agondanou, J.-H.; Dupont, N.; Godard, A.-M.; Stiebing, S.; Rochais, C.; Fabis, F.; Dallemagne, P.; Bureau, R.; Rault, S. Virtual Screening Discovery of New Acetylcholinesterase Inhibitors Issued from CERMN Chemical Library. J. Chem. Inf. Model. 2010, 50, 422–428.

(21)    Sobrio, F.; Lemaitre, S.; Hinsberger, A.; Barré, L.; Rousseau, B.; Rault, S. Simultaneous Tritium Labelling of Two Potent 5-HT4 Ligands. Eur. J. Med. Chem. 2010, 45, 1263–1265.

(20)    Rochais, C.; Rault, S.; Dallemagne, P. Intramolecular Cyclisation of β-Aryl-β-Amino Acids in the Design of Novel Heterocyclic Systems with Therapeutic Interest: An Unfailing Source of Diversity. Curr. Med. Chem. 2010, 17, 4342–4369.

(19)    Primas, N.; Bouillon, A.; Rault, S. Recent Progress in the Synthesis of Five-Membered Heterocycle Boronic Acids and Esters. Tetrahedron 2010, 66, 8121–8136.

(18)    Perri, V.; Rochais, C.; Sopkova-de Oliveira Santos, J.; Legay, R.; Cresteil, T.; Dallemagne, P.; Rault, S. Hydrogenative Desulphurization of Thienopyrrolizinones: An Easy and Selective Access to (Z)-Phenethylidenepyrrolizinones with in Vitro Cytotoxic Activity. Eur. J. Med. Chem. 2010, 45, 1146–1150.

(17)    Mercey, G.; Legay, R.; Lohier, J.-F.; Santos, J. S. O.; Levillain, J.; Gaumont, A.-C.; Gulea, M. Synthesis of 3-Amino-Thiochromanes from 4-Benzyl 2-Thiazolines, via an Unprecedented Intramolecular Electrophilic Aromatic Substitution. Org. Biomol. Chem. 2010, 8, 2520–2521.

(16)    Malzert-Fréon, A.; Saint-Lorant, G.; Hennequin, D.; Gauduchon, P.; Poulain, L.; Rault, S. Influence of the Introduction of a Solubility Enhancer on the Formulation of Lipidic Nanoparticles with Improved Drug Loading Rates. Eur. J. Pharm. Biopharm. 2010, 75, 117–127.

(15)    Malzert-Fréon, A.; Hennequin, D.; Rault, S. Partial Least Squares Analysis and Mixture Design for the Study of the Influence of Composition Variables on Lipidic Nanoparticle Characteristics. J. Pharm. Sci. 2010, 99, 4603–4615.

(14)    Lozano, S.; Poezevara, G.; Halm-Lemeille, M. P.; Lescot-Fontaine, E.; Lepailleur, A.; Bissell-Siders, R.; Crémilleux, B.; Rault, S.; Cuissart, B.; Bureau, R. Introduction of Jumping Fragments in Combination with QSARs for the Assessment of Classification in Ecotoxicology. J. Chem. Inf. Model. 2010, 50, 1330–1339.

(13)    Lozano, S.; Lescot, E.; Halm, M.-P.; Lepailleur, A.; Bureau, R.; Rault, S. Prediction of Acute Toxicity in Fish by Using QSAR Methods and Chemical Modes of Action. J. Enzyme Inhib. Med. Chem. 2010, 25, 195–203.

(12)    Lozano, S.; Halm-Lemeille, M. P.; Lepailleur, A.; Rault, S.; Bureau, R. Consensus QSAR Related to Global or MOA Models: Application to Acute Toxicity for Fish. Mol. Inform. 2010, 29, 803–813.

(11)     Lohier, J. F.; Caruso, A.; Sopková-De Oliveira Santos, J.; Lancelot, J. C.; Rault, S. Tert-Butyl 6-Bromo-1,4-Dimethyl-9H-Carbazole-9-Carboxylate. Acta Crystallogr. Sect. E Struct. Reports Online 2010, 66, 1971–1972.

(10)     Lepailleur, A.; Lemaître, S.; Feng, X.; Santos, J. S. D. O.; Delagrange, P.; Boutin, J.; Renard, P.; Bureau, R.; Rault, S. Receptor- And Ligand-Based Study on Novel 2,2'-Bithienyl Derivatives as Non-Peptidic AANAT Inhibitors. J. Chem. Inf. Model. 2010, 50, 446–460.

(9)     Lefebvre, V.; Cailly, T.; Fabis, F.; Rault, S. Two-Step Synthesis of Substituted 3-Aminoindazoles from 2-Bromobenzonitriles. J. Org. Chem. 2010, 75, 2730–2732.

(8)     Laine, E.; Goncalves, C.; Karst, J. C.; Lesnard, A.; Rault, S.; Tang, W.-J.; Malliavin, T. E.; Ladant, D.; Blondel, A. Use of Allostery to Identify Inhibitors of Calmodulin-Induced Activation of Bacillus Anthracis Edema Factor. Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 11277–11282.

(7)     Houllier, N.; Lasne, M. C.; Bureau, R.; Lestage, P.; Rouden, J. Synthesis of a Cytisine/epibatidine Hybrid: A Radical Approach. Tetrahedron 2010, 66, 9231–9241.

(6)     Dubost, E.; Magnelli, R.; Cailly, T.; Legay, R.; Fabis, F.; Rault, S. General Method for the Synthesis of Substituted Phenanthridin-6(5H)-Ones Using a KOH-Mediated Anionic Ring Closure as the Key Step. Tetrahedron 2010, 66, 5008–5016.

(5)     Cailly, T.; Dumas, N.; Millet, P.; Lemaître, S.; Fabis, F.; Charnay, Y.; Rault, S. Synthesis and Characterization of a Iodine-125-Labeled pyrrolo[1,2-A] thieno[3,2-E]pyrazine and Evaluation as a Potential 5-HT4R SPECT Tracer. Eur. J. Med. Chem. 2010, 45, 5465–5467.

(4)     Burzicki, G.; Voisin-Chiret, A. S.; Santos, J. S. D. O.; Rault, S. Synthesis of New [2,3':6',3'']terpyridines Using Iterative Cross-Coupling Reactions. Synthesis (Stuttg). 2010, 2804–2810.

(3)     Bureau, R.; Boulouard, M.; Dauphin, F.; Lezoualc’h, F.; Rault, S. Review of 5-HT4R Ligands: State of Art and Clinical Applications. Curr. Top. Med. Chem. 2010, 10, 527–553.

(2)     Brossard, D.; Elkihel, L.; Khalid, M.; Rault, S. Synthesis of 6-Aryl-Substituted Cholesterol Derivatives from 3-Acetoxy-6-Iodocholest-5-Ene and Arylboronic Acids Promoted by Palladium-Catalyzed Cross-Coupling. Synlett 2010, 215–218.

(1)     Brossard, D.; El Kihel, L.; Clément, M.; Sebbahi, W.; Khalid, M.; Roussakis, C.; Rault, S. Synthesis of Bile Acid Derivatives and in Vitro Cytotoxic Activity with pro-Apoptotic Process on Multiple Myeloma (KMS-11), Glioblastoma Multiforme (GBM), and Colonic Carcinoma (HCT-116) Human Cell Lines. Eur. J. Med. Chem. 2010, 45, 2912–2918.

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Dernière modification : 13 septembre 2015



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