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Publications

Publications 2019


(175)     Thirumaran, S.-L.; Lepailleur, A.; Rochais, C. Structure-Activity Relationships of Serotonin 5-HT7 Receptors Ligands: A Review. Eur. J. Med. Chem. 2019, 183, 111705.
https://doi.org/10.1016/j.ejmech.2019.111705

(174)     Lanthier, C.; Payan, H.; Liparulo, I.; Hatat, B.; Lecoutey, C.; Since, M.; Davis, A.; Bergamini, C.; Claeysen, S.; Dallemagne, P.; Bolognesi, M.L.; Rochais, C. Novel Multi Target-Directed Ligands Targeting 5-HT4 Receptors with in Cellulo Antioxidant Properties as Promising Leads in Alzheimer’s Disease. Eur. J. Med. Chem. 2019, 182, 111596.
https://doi.org/10.1016/j.ejmech.2019.111596.

(173)     Ceramella, J.; Caruso, A.; Occhiuzzi, M. A.; Iacopetta, D.; Barbarossa, A.; Rizzuti, B.; Dallemagne, P.; Rault, S.; El-Kashef, H.; Saturnino, C.; Grande, F.; Sinicropi, M.S. Benzothienoquinazolinones as New Multi-Target Scaffolds: Dual Inhibition of Human Topoisomerase I and Tubulin Polymerization. Eur. J. Med. Chem. 2019, 181, 111583.
https://doi.org/10.1016/j.ejmech.2019.111583.

(172)     Riva, C.; Suzanne, P.; Charpentier, G.; Dulin, F.; Halm-Lemeille, M.-P.; Sopkova-de Oliveira Santos, J. In Silico Chemical Library Screening and Experimental Validation of Novel Compounds with Potential Varroacide Activities. Pestic. Biochem. Physiol. 2019, 160, 11–19.
doi: 10.1016/j.pestbp.2019.05.012.

(171)     Toublet, F.-X.; Lecoutey, C.; Lalut, J.; Hatat, B.; Davis, A.; Since, M.; Corvaisier, S.; Freret, T.; Sopkova de Oliveira Santos, J.; Claeysen, S.; Boulouard, M.; Dallemagne, P.; Rochais, C. Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer’s Disease. Molecules 2019, 24, 2786.
doi : 10.3390/molecules24152786.

(170)     Croft, R. A.; Dubois, M. A. J.; Boddy, A. J.; Denis, C.; Lazaridou, A.; Voisin-Chiret, A. S.; Bureau, R.; Choi, C.; Mousseau, J. J.; Bull, J. A. Catalytic Friedel-Crafts Reactions on Saturated Heterocycles and Small Rings for Sp 3 -Sp 2 Coupling of Medicinally Relevant Fragments. European J. Org. Chem. 2019, 2019, 5385–5395.
doi : 10.1002/ejoc.201900498.

(169)     Ceramella, J.; Loizzo, M. R.; Iacopetta, D.; Bonesi, M.; Sicari, V.; Pellicanò, T. M.; Saturnino, C.; Malzert-Fréon, A.; Tundis, R.; Sinicropi, M. S. Anchusa Azurea Mill. (Boraginaceae) Aerial Parts Methanol Extract Interfering with Cytoskeleton Organization Induces Programmed Cancer Cells Death. Food Funct. 2019, 10, 4280–4290.
doi : 10.1039/C9FO00582J.

(168)    Sergeant, N.; Vingtdeux, V.; Eddarkaoui, S.; Gay, M.; Evrard, C.; Le Fur, N.; Laurent, C.; Caillierez, R.; Obriot, H.; Larchanché, P.-E.; Farce, A.; Coevoet, M.; Carato, P.; Kouach, M.; Descat, A.; Dallemagne, P.; Buée-Scherrer, V.; Blum, D.; Hamdane, M.; Buée, L.; Melnyk, P. New Piperazine Multi-Effect Drugs Prevent Neurofibrillary Degeneration and Amyloid Deposition, and Preserve Memory in Animal Models of Alzheimer’s Disease. Neurobiol. Dis. 2019, 129, 217–233.
doi : 10.1016/j.nbd.2019.03.028.

(167)     Hatat, B.; Yahiaoui, S.; Lecoutey, C.; Davis, A.; Freret, T. A Novel in Vivo Anti-Amnesic Agent , Specially Designed to Express Both Acetylcholinesterase ( AChE ) Inhibitory , Serotonergic Subtype 4 Receptor ( 5-HT 4 R ) Agonist and Serotonergic Subtype 6 Receptor ( 5-HT 6 R ) Inverse Agonist Activities , With a Potential Interest Against Alzheimer’s Disease. Front. Aging Neurosci. 2019, 11, 148.
doi: 10.3389/fnagi.2019.00148.

(166)     Laggoun, F.; Dardelle, F.; Dehors, J.; Falconet, D.; Driouich, A.; Rochais, C.; Dallemagne, P.; Lehner, A.; Mollet, J. A Chemical Screen Identifies Two Novel Small Compounds That Alter Arabidopsis Thaliana Pollen Tube Growth. BMC Plant Biol. 2019, 19, 152.
doi: 10.1186/s12870-019-1743-9.

(165)     Smeralda, W.; Since, M.; Corvaisier, S.; Legay, R.; Voisin-Chiret, A.-S.; Malzert-Freon, A. Microplate Assay for Lipophilicity Determination Using Intrinsic Fluorescence of Drugs: Application to a Promising Anticancer Lead, Pyridoclax. Eur. J. Pharm. Sci. 2019, 131, 75–83.
doi: 10.1016/j.ejps.2019.02.010.

(164)     Denis, C.; Dubois, M. A. J.; Voisin-Chiret, A. S.; Bureau, R.; Choi, C.; Mousseau, J. J.; Bull, J. A. Synthesis of 3,3-Diarylazetidines by Calcium(II)-Catalyzed Friedel–Crafts Reaction of Azetidinols with Unexpected Cbz Enhanced Reactivity. Org. Lett. 2019, 21, 300–304.
doi : 10.1021/acs.orglett.8b03745

(163)     Fersing, C.; Basmaciyan, L.; Boudot, C.; Pedron, J.; Hutter, S.; Cohen, A.; Castera-Ducros, C.; Primas, N.; Laget, M.; Casanova, M.; Bourgeade-Delmas, S.; Piednoel, M.; Sournia-Saquet, A.; Belle Mbou, V.; Courtioux, B.; Boutet-Robinet, É.; Since, M.; Milne, R.; Wyllie, S.; Fairlamb, A. H.; Valentin, A.; Rathelot, P.; Verhaeghe, P.; Vanelle, P.; Azas, N. Nongenotoxic 3-Nitroimidazo[1,2- a ]Pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity. ACS Med. Chem. Lett. 2019, 10, 34–39.
doi : 10.1021/acsmedchemlett.8b00347

(162)     Lalut, J.; Santoni, G.; Karila, D.; Lecoutey, C.; Davis, A.; Nachon, F.; Silman, I.; Sussman, J.; Weik, M.; Maurice, T.; Dallemagne, P.; Rochais, C. Novel Multitarget-Directed Ligands Targeting Acetylcholinesterase and S1 Receptors as Lead Compounds for Treatment of Alzheimer’s Disease: Synthesis, Evaluation, and Structural Characterization of Their Complexes with Acetylcholinesterase. Eur. J. Med. Chem. 2019, 162, 234–248.
doi: 10.1016/j.ejmech.2018.10.064

(161)     Thieulent, C. J.; Hue, E. S.; Fortier, C. I.; Dallemagne, P.; Zientara, S.; Munier-Lehmann, H.; Hans, A.; Fortier, G. D.; Pitel, P.-H.; Vidalain, P.-O.; Pronost, S. L. Screening and Evaluation of Antiviral Compounds against Equid Alpha-Herpesviruses Using an Impedance-Based Cellular Assay. Virology 2019, 526, 105–116.
doi: 10.1016/j.virol.2018.10.013

(160)     Tournier, B. B.; Tsartsalis, S.; Rigaud, D.; Fossey, C.; Cailly, T.; Fabis, F.; Pham, T.; Grégoire, M.-C.; Kövari, E.; Moulin-Sallanon, M.; Savioz, A.; Millet, P. TSPO and Amyloid Deposits in Sub-Regions of the Hippocampus in the 3xTgAD Mouse Model of Alzheimer’s Disease. Neurobiol. Dis. 2019, 121, 95–105.
doi : 10.1016/j.nbd.2018.09.022




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Dernière modification : 5 novembre 2019



Université de Caen Normandie
CERMN Centre détudes et de recherche sur le médicament de Normandie
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