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MinOmics

The joint CERMN / GREYC Minomics programme is a reworking of technologies based on the notion of contrast. The aim is to understand the correspondence between a pharmacological profile · in this case polypharmacology · and the chemical patterns present in the structures. The analysis is backed up with the development of 2D and 3D imagery software, together with distance integration and multi-conformational reasoning. These techniques have been developed from the comparative analytical methods of pharmacophores which are the source of laboratory 5-HT ligands.
An illustration of this may be found in Dr J.P. Métivier / Dr A. Lepailleur / Pr R. Bureau‘s preliminary study into kinases · GSK-PKIS for data on CHEMBl · with a 2D analysis of active patterns within one family as well as their correspondence with all types of kinases. The present illustration does not integrate distance.
An illustration of this may be found in Dr J.P. Métivier / Dr A. Lepailleur / Pr R. Bureau ‘s preliminary study into kinases  · GSK-PKIS for data on ChEMBL · with a 2D analysis of active patterns within one family as well as their correspondence with all types of kinases. The present illustration does not integrate distance.

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Last update : July 4, 2016


CONTACT

Pr Ronan Bureau
+33 (0)2 31 56 68 20
ronan.bureau@unicaen.fr

Université de Caen Normandie
CERMN Centre détudes et de recherche sur le médicament de Normandie
Boulevard Becquerel | 14032 Caen Cedex | France